@article {216,
	title = {COMPUTERS IN MEDICINAL CHEMISTRY. MOLECULAR MODELING AND CALCULATION OF THE STRUCTURE-CORRELATED PARAMETERS DESCRIBING SKIN PERMEABILITY OF THEAFLAVONOIDS},
	journal = {Problems of Education in the 21st Century },
	volume = {11},
	year = {2009},
	month = {May/2009},
	type = {Original article},
	chapter = {139-150},
	abstract = {The application of computational technique for predicting biological activity of chemicals plays an important role in development and design of new drugs. Being now a routine approach in medicinal chemistry, the method still encounters difficulties in teaching medical science students.
 In this paper the project of introduction the students to the computational tools and approaches usually used in pharmacy and medicine is presented. The project involves estimation of the skin permeability of theaflavonoids in respect to their usefulness in topical application. Topical application of flavonoids for inhibition of skin tumor is preferred because flavonoids are poorly absorbed from intestines and are decomposed by intestinal microorganisms.},
	keywords = {molecular modeling, theaflavonoids},
	issn = {1822-7864},
	url = {http://oaji.net/articles/2014/457-1392408980.pdf},
	author = {Marek Persona and Andrzej Persona and Tomasz G{\k e}ca and Agnieszka Kaczor and Dariusz Matosiuk}
}
@article {172,
	title = {IMAGES AND COMPUTATIONAL METHODS IN MOLECULAR MODELING EDUCATION},
	journal = {Problems of Education in the 21st Century },
	volume = {9},
	year = {2008},
	month = {November/2008},
	type = {Original article},
	chapter = {17-23},
	abstract = {The way as Chemistry is boarded in the schools can contribute for the misconceptions, a time that the concepts are presented of form purely theoretician (and, therefore, tedious for the majority of the pupils), as something that must be memorize and that it is not apply the different aspects of the daily life. So, the aim of this work is to provide the understanding of the chemical world that underlies everything around us by introducing basic chemical concepts and their everyday applications. So that, some specific topics will be presented and they were selected according to their relevance and their ability to be presented in lessons on molecular modeling. This strategy is based on the use of images and free graphics programs employed in chemistry successfully, as the visual effects help the students to {\textquotedblleft}see{\textquotedblright} abstract descriptions in a concrete form. According to the results obtained by using this methodology, we can conclude that the use of images and computational techniques help the presentation of scientific topics and motivate and facilitate the "chemistry communication".},
	keywords = {misconceptions, molecular modeling, science education},
	issn = {1822-7864},
	url = {http://oaji.net/articles/2014/457-1392297937.pdf},
	author = {Agnaldo Arroio and K{\'a}thia Hon{\'o}rio}
}
