The goal of general chemistry and biochemistry – teach students to use their knowledge about chemical structure of organism and molecular processes. To better understand explanations and to prognosticate processes students are given, information presented on other courses. As time dedicated for chemistry course for first year students of RSU is reduced, use of critical thinking strategies in starting period of study process increases probability of achieving positive results. By organizing study process at the beginning of semester, students are introduced to detailed plan thus giving an opportunity to organize their own time according to previous learning experience. Students are provided with thorough study material both in printed and electronic form thus allowing them to find more time for fact analysis, problem solving and relation finding. By stepping away from the traditional routine, the proportion between lectures and practical lessons was changed in favour of practical lessons. Gained experience allows concluding that intensive work with small groups, by introducing students to different approaches to information analysis, graphical systematization of information, development of dialog skills and other methods is effective and worth developing.