RESTRAIN OF FEAR: PARTICIPATION OF GABA NEUROTRANSMITTER SYSTEM
| Title | RESTRAIN OF FEAR: PARTICIPATION OF GABA NEUROTRANSMITTER SYSTEM |
| Publication Type | Journal Article |
| Year of Publication | 2013 |
| Authors | Shulgina, GI, Berezhnaya, DA, Parfentyev, NA |
| Journal | Problems of Psychology in the 21st Century |
| Volume | 6 |
| Start Page | 71-85 |
| Date Published | July/2013 |
| Type of Article | Original article |
| ISSN | 2029-8587 |
| Other Numbers | ICID: 1059501 |
| Keywords | disinhibition, freezing, inhibition, training |
| Abstract | In experiences on rats in the conditions of free behavior at development of a conditioned of passive avoidanсe reflex (the first series) and a defensive reflex and a conditional inhibition (the second series) it is revealed, and elaboration of internal inhibition and Phenibut – a nonspecific agonist of GAMKA and GAMKB receptors cause in experimental animals weakening of freezing arising in a dangerous situation, and a disinhibition of research behavior. Results of experiences in the accounting of data of the literature allow to assume that both factors, and elaboration of internal inhibition, and Phenibut weaken freezing – the phenomenon used in experiments as a biological analog of fear, owing to increase of level of activity of the GABA neurotransmitter system of a brain. |
| URL | https://oaji.net/articles/2014/444-1400266890.pdf |
| DOI | 10.33225/ppc/13.06.71 |
| Refereed Designation | Refereed |
| Full Text |