E-learning has become an integral part of the present day tertiary education, not only within the framework of combined, but, to an increasingly larger extent, also of full-time study modes. However, its deployment on a large scale resulted in the emergence of many problems which shall become a subject of research and investigation. The present study reflects the attitudes of university students toward e-learning within their course of study, and submits partial results of the research investigation implemented throughout the years 2007 to 2011. The hereinabove described survey research focused on monitoring and evaluating students` attitudes to the teaching through e-learning based on the use of electronic study supports enriched with multimedia elements. The research data collection was carried out by means of a non-standardized research questionnaire and the data were subsequently analysed using nonparametric statistical methods. Selected outputs of the research, focused primarily on the assessment of the level of students’ satisfaction with the organization of teaching through e-learning, and on the identification of the elements of electronic study materials preferred by the students, are the subject of this study.